王冰 项目研究员，团队负责人
博士生导师，中科院海外高层次人才
王冰博士于2009年本科毕业于中国科学技术大学高分子科学与工程系，之后在中国科学院化学研究所有机固体实验室王树研究员课题组学习并获得博士学位，主要开展水溶性共轭聚合物的设计合成及其在生物成像、治疗和生理调控等领域的应用。2015年至2020年，在加州大学圣巴巴拉分校从事博士后研究工作，合作导师是化学与生物化学系Guillermo C. Bazan教授以及力学工程系Sumita Pennathur教授，主要开展嵌膜共轭寡聚电解质的设计、合成以及在光活性抗菌及生物催化中的应用，同时开展血糖持续监测的研究。2020年11月加入中国科学院宁波材料技术与工程研究所，慈溪生物医学工程研究所，担任项目研究员，组建有机光学诊疗材料与技术团队，致力于疾病健康相关的光学诊断和治疗研究，重点开发新一代的持续血糖监测体系与技术、生物荧光探针以及针对病原微生物的光动力和光热治疗等。博士期间曾获得博士研究生国家奖学金和中国科学院院长优秀奖，博后期间获得美国糖尿病协会博士后基金资助。迄今在国际著名期刊上共发表学术论文20多篇，其中在Adv. Mater.、Angew. Chem. Int. Ed.、J. Am. Chem. Soc共发表10多篇。
研究方向：
- 稳定的持续血糖监测
- 有机光功能材料的设计合成
- 病原微生物的光学诊疗
- 亚细胞结构的稳定成像
工作经历：
2020.11-至今 中国科学院宁波材料技术与工程研究所，慈溪生物医学与工程研究所，项目研究员
2015.9-2020.11 美国加州大学圣塔芭芭拉分校，博士后
教育背景：
2009.9-2015.7 中国科学院化学研究所，博士
2005.9-2009.6 中国科学技术大学，本科
发表文章：
- Changsheng Du, Dong Gao*, Mengshi Gao, Hongbo Yuan, Xiaoning Liu, Bing Wang*, Chengfen Xing*. Property Regulation of Conjugated Oligoelectrolytes with Polyisocyanide to Achieve Efficient Photodynamic Antibacterial Biomimetic Hydrogels, ACS Appl. Mater. Interfaces 2021, 13, 27955–27962.
- Hyunjin Kim, Dan Cohen, Bing Wang*, Bridget N. Queenan, Guillermo C. Bazan, Sumita Pennathur*. Integration of buried dual-junction photodetection with ratiometric FRET-based biosensing: Results and design considerations, Sensor. Actuat. A-Phys. 2020, 315, 112364.
- Bing Wang, Kuang-Hua Chou, Bridget N. Queenan, Sumita Pennathur*, Guillermo C. Bazan*. Molecular Design of a New Diboronic Acid for the Electrohydrodynamic Monitoring of Glucose. Angew. Chem. Int. Ed. 2019, 58, 10612-10615.
- Bing Wang, Bridget N. Queenan, Shu Wang, K. Peter R. Nilsson*, Guillermo C. Bazan*. Precisely Defined Conjugated Oligoelectrolytes for Biosensing and Therapeutics. Adv. Mater. 2019, 31, 1806701.
- Bing Wang, Stephanie L Fronk, Zachary D Rengert, Jakkarin Limwongyut, Guillermo C Bazan*. Conjugated Oligoelectrolytes: Materials for Acceleration of Whole Cell Biocatalysis. Chem. Mater. 2018, 30, 5836-5840.
- Bing Jia, Xin Zhang, Bing Wang, Muhua Chen, Fengting Lv, Shu Wang,* Fan Wang*. Dual-Modal Probe Based on Polythiophene Derivative for Pre- and Intraoperative Mapping of Lymph Nodes by SPECT/Optical Imaging. ACS Appl. Mater. Interfaces 2018, 10, 6646-6651. (共一)
- Bing Wang, Guangxue Feng, Martin Seifrid, Ming Wang, Bin Liu*, Guillermo C. Bazan*. Antibacterial Narrow-Band-Gap Conjugated Oligoelectrolytes with High Photothermal Conversion Efficiency. Angew. Chem. Int. Ed. 2017, 56, 16063-16066.
- Bing Wang, Chenyao Nie, Libing Liu, Fengting Lv, Shu Wang*. Selective Biocompatibility and Responsive Imaging Property of Cationic Conjugated Polyelectrolyte to Cancer Cells. Chin. Chem. Lett. 2017, 28, 1975-1978.
- Bing Wang, Ming Wang, Alexander Mikhailovsky, Shu Wang, Guillermo C. Bazan*. A Membrane-Intercalating Conjugated Oligoelectrolyte with High-Efficiency Photodynamic Antimicrobial Activity. Angew. Chem. Int. Ed. 2017, 56, 5031-5034.
- Bing Wang, Huanxiang Yuan, Zhang Liu, Chenyao Nie, Libing Liu, Fengting Lv, Yilin Wang, Shu Wang*. Cationic Oligo(p-phenylene vinylene) Materials for Combating Drug Resistance of Cancer Cells by Light Manipulation. Adv. Mater. 2014, 26, 5986-5990.
- Bing Wang, Jinzhao Song, Huanxiang Yuan, Chenyao Nie, Fengting Lv, Libing Liu, Shu Wang*. Multicellular Assembly and Light-Regulation of Cell-Cell Communication by Conjugated Polymer Materials. Adv. Mater. 2014, 26, 2371-2375.
- Bing Wang, Chunlei Zhu, Libing Liu, Fengting Lv, Qiong Yang, Shu Wang*. Synthesis of a New Conjugated Polymer for Cell Membrane Imaging by Using an Intracellular Targeting Strategy. Poly. Chem. 2013, 4, 5212-5215.
- Bing Wang, Huanxiang Yuan, Chunlei Zhu, Qiong Yang*, Fengting Lv, Libing Liu, Shu Wang*. Polymer-drug Conjugates for Intracellar Molecule-targeted Photoinduced Inactivation of Protein and Growth Inhibition of Cancer Cells. Sci. Rep. 2012, 2, 766.
- Bing Wang, Qiong Yang*, Libing Liu, Shu Wang*. Direct Energy Transfer From Conjugated Polymer to DNA Intercalated dye: Label-free Fluorescent DNA Detection. Colloids Surf. B: Biointerfaces 2011, 85, 8-11.